South Staffordshire Joint FormularyCannock Chase Clinical Commissioning Group East Staffordshire Clinical Commissioning Group South East Staffordshire and Seisdon Peninsula Clinical Commissioning Group Stafford and Surrounds Clinical Commissioning Group
Preservative-free (PF) formulations - Preservative intolerance should be diagnosed by an ophthalmologist. If PF formulation is warranted, proprietary preservative-free formulations (often available as unit dose preparations) should be prescribed if at all possible. Manufactured “specials” are unlicensed and almost invariably cost significantly more. PF formulations are appropriate, for example when a patient wears soft contact lenses or daily disposable contact lenses and wearing glasses instead is not a viable option such as for long courses OR where patient shows signs of preservative toxicity sometimes seen with multiple daily administrations.
Anti-infective eye preparations
Chloramphen_Eye Dps 0.5% Chloramphen_Eye Oint 1% Chloramphen_PF Eye Dps 0.5% - preservative free eye drops prescribe as Eykappo as more cost effective
Chloramphenicol eye drops and ointment are Self Care Medicine- Available OTC for self-care. (Please note exceptions may apply)
Updated advice for healthcare professionals on Chloramphenicol Eye Drop prescribing in children aged 0-2 years
- In March 2021 some licences for chloramphenicol eye drops containing borax/boric acid buffers were updated to restrict use in children younger than 2 years of age
- MHRA has now reviewed the available evidence and sought independent expert evidence and concluded that the benefits of chloramphenicol eye drops containing borax or boric acid outweigh the potential risks for children, including those aged 0 to 2 years
- Hence, chloramphenicol eye drops can now be safely administered to children aged 0 to 2 years where antibiotic eye drop treatment is indicated
Urgently refer all patients with suspected herpes simplex to the hospital eye department
DISCONTINUED: GSK, the sole supplier of aciclovir eye ointment, plans to discontinue it from the worldwide market in 2018. Stock is anticipated to continue to be available in the UK until the end of June 2019, subject to demand.
An alternative agent is Ganciclovir 0.15% w/w eye gel (licensed for acute herpetic keratitis).
Non Formulary Items
Econazole 1% eye drops
Foscarnet intravitreal injection
Ganciclovir 0.15% ophthalmic gel (Virgan®)
Ganciclovir intravitreal injection
Gentamicin single use (Minims® Gentamicin Sulphate)
This is a Specialised Drug which would not be routinely commissioned by CCGs for Cystic Fibrosis. This would go through a South Staffs CCGs Individual Funding Request (IFR)
Miconazole 1% eye drops
Neomycin Sulphate with antibacterials (Neosporin®)
Ofloxacin Eye drops (Exocin®)
Polymyxin B Sulphate eye ointment (Polyfax®)
Propamidine Isetionate (Brolene®)
Self Care Medicine -Available OTC for self-care.
(Please note exceptions may apply)
Trifluorothymidine eye drops
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Link to adult BNF
Link to children's BNF
Link to SPCs
Scottish Medicines Consortium
High Cost Medicine
Cancer Drugs Fund
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Drugs which require special consideration. These are drugs for Consultant Prescribing ONLY. They should not be prescribed in Primary Care.
Drugs that should be initiated by a Specialist but are suitable for continuation in Primary Care. For some drugs there may be a Ricad in place to aid the transition to primary care.
Drugs that should be initiated by a Specialist but are suitable for continuation in Primary Care but also require and ESCA (Shared Care Agreement)
Suitable first-line drugs for implementation in Primary Care