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South Staffordshire Joint Formulary
Cannock Chase Clinical Commissioning Group
East Staffordshire Clinical Commissioning Group
South East Staffordshire and Seisdon Peninsula Clinical Commissioning Group
Stafford and Surrounds Clinical Commissioning Group
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 Formulary Chapter 11: Eye - Full Chapter
Notes:

Preservative-free (PF) formulations - Preservative intolerance should be diagnosed by an ophthalmologist. If PF formulation is warranted, proprietary preservative-free formulations (often available as unit dose preparations) should be prescribed if at all possible. Manufactured “specials” are unlicensed and almost invariably cost significantly more.  PF formulations are appropriate, for example when a patient wears soft contact lenses or daily disposable contact lenses and wearing glasses instead is not a viable option such as for long courses OR where patient shows signs of preservative toxicity sometimes seen with multiple daily administrations.

 Details...
11.08  Expand sub section  Miscellaneous ophthalmic preparations
11.08.01  Expand sub section  Tear deficiency, ocular lubricants, and astringents
Hypromellose 0.5% eye drops
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First Choice
Green

Please prescribe generically

         

    Self Care Self Care Medicine-Available OTC for self care

         

 
Carbomer 980 0.2% (Clinitas)
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Second Choice
Green

Prescribe as Clinitas carbomer_eye gel 0.2%

Self Care Self Care Medicine-Available OTC for self-care. 

                                        

 

 

 
   
Carmellose sodium
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Third Choice
Green

Carmellose Sod_Eye Dps 0.5%
Carmellose Sod_Eye Dps 0.5% 0.4ml Ud
Carmellose Sod_Eye Dps 1% 0.4ml Ud

 

Self Care Self Care Medicine-Available OTC for self care.

 

 

 
   
Liquid Paraffin (Xailin Night )
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Formulary
Green

Xailin Night Ointment 5g

This is the preferred cost effective brand of liquid paraffin eye ointment.

Self Care Self Care Medicine-Available OTC for self care.

 

 
   
Liquid Paraffin (HYLO NIGHT)
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Formulary
Green

HYLO NIGHT eye ointment preservative free (formerly known as Vita-POS Paraf Eye Oint P/F)

This is another preferred cost effective brand of liquid paraffin eye ointment

Self Care Self Care Medicine-Available OTC for self care.

 
   
Ciclosporin  (Ikervis)
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Formulary
Amber

Ciclosporin for treating dry eye disease that has not improved  despite treatment with artificial tears

Prescribing should be reviewed by a specialist every 6 months and if there is no improvement treatment should be stopped

 
Link  TA369 : Ciclosporin for treating dry eye disease that has not improved despitetreatment with artificial tears
   
Hypromellose (Evolve)
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Formulary
Green

0.3% eye drops preservative free

Self Care Self Care Medicine-Available OTC for self care.

 

 
   
Sodium hyaluronate (Artelac Rebalance)
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Formulary
Green

0.15% eye drops preservative free

Self Care Self Care Medicine-Available OTC for self care.

 


 

 
   
Sodium hyaluronate (Evolve HA)
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Formulary
Green

0.2% eye drops preservative free

Self Care Self Care Medicine-Available OTC for self care.

 

 
   
11.08.02  Expand sub section  Ocular diagnostic and peri-operative preparations and photodynamic treatment
11.08.02  Expand sub section  Subfoveal choroidal neovascularisation
Aflibercept (Eylea)
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Formulary
Red
High Cost Medicine
CCG
BlueTeq

Restriction: In line with NICE Guidance only

 
Link  NICE TA294: Aflibercept solution for injection for treating wet age‑related macular degeneration
Link  NICE TA305: Aflibercept for treating visual impairment caused by macular oedema secondary to central retinal vein occlusion
Link  NICE TA346: Aflibercept for treating diabetic macular oedema
Link  NICE TA409 : Aflibercept for treating visual impairment caused by macular oedema after branch retinal vein occlusion
Link  NICE TA486: Aflibercept for treating choroidal neovascularisation
   
BrolucizumabBlack Triangle (Beovu)
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Formulary
Red
High Cost Medicine
CCG
BlueTeq

Restriction: In line with NICE Guidance only

 
Link  NICE TA672: Brolucizumab for treating wet age-related macular degeneration
   
Ranibizumab (Lucentis)
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Formulary
Red
High Cost Medicine
CCG
BlueTeq

Restriction: In line with NICE Guidance only

 
Link  NICE TA155 - Ranibizumab and pegaptanib for the treatment of age-related macular degeneration
Link  NICE TA274: Ranibizumab for treating diabetic macular oedema
Link  NICE TA283: Ranibizumab for treating visual impairment caused by macular oedema secondary to retinal vein occlusion
Link  NICE TA298: Ranibizumab for treating choroidal neovascularisation associated with pathological myopia
   
11.08.02  Expand sub section  Vitreomacular traction to top
Ocriplasmin (Jetrea)
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Restricted Drug Restricted
Red
 
Link  NICE TA297: Ocriplasmin for treating vitreomacular traction
   
 ....
 Non Formulary Items
Carmellose sodium  (Celluvisc)

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Non Formulary 1% eye drops 0.4ml unit dose preservative free
0.5% eye drops 0.4ml unit dose preservative free

Please prescribe generic carmellose preparations as per formulary
 
Acetylcysteine 5% eye drops

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Non Formulary
 
Acetylcysteine 5% with Hypromellose 0.35%  (Ilube)

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Non Formulary
 
Bevacizumab intravitreal injection  (Avastin)

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Non Formulary
 
Carbomers  (Blephagel)

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Non Formulary 0.35% eye gel
0.36% eye gel preservative free

Prescribe as Clinitas
 
Carbomers  (GelTears)

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Non Formulary Non formulary instead prescribe as clinitas carbomer eye drops
 
Carbomers  (liquivisc)

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Non Formulary Non formulary instead prescribe as clinitas carbomer eye drops
 
Carbomers  (Viscotears)

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Non Formulary Non formulary instead prescribe as clinitas carbomer eye drops
 
Carmellose Sodium  (Carmize)

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Non Formulary Carmize 0.5% eye drops
Carmize 1% eye drops
Carmize 1% unit dose 0.4ml unit dose pf

Please prescribe generic carmellose preparations as per formulary
 
Carmellose sodium  (Cellusan light)

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Non Formulary 0.5% Preservative free

Please prescribe generic carmellose preparations as per formulary
 
Carmellose sodium  (Cellusan)

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Non Formulary Cellusan 1% eye drops Unit dose preservative free
Cellusan 1% eye drops 10ml preservative free

Please prescribe generic carmellose preparations as per fomulary
 
Carmellose sodium  (Evolve Carmellose)

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Non Formulary 0.5% eye drops Preservative free

Please prescribe generic carmellose as per formulary
 
Carmellose sodium  (Lumecare)

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Non Formulary Lumecare Advance Carmellose 0.5% eye drops
Lumecare Singles 0.5% Carmellose 0.4ml unit dose preservative free

Please prescribe generic carmellose preparations as per formulary
 
Carmellose sodium  (Melophthal)

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Non Formulary 1% unit dose eye drops preservative free
0.5% unit dose eye drops preservative free

Please prescribe generic carmellose preparations as per formulary
 
Carmellose sodium  (Optho-Lique)

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Non Formulary Optho-Lique 0.5% eye drops
Optho-Lique Forte 1% eye drops

Please prescribe generic carmellose preparations as per formulary
 
Carmellose sodium  (Optive)

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Non Formulary Optive 0.5% eye drops
Optive Plus 0.5% eye drops

Please prescribe generic carmellose preparations as per formulary
 
Carmellose sodium  (Xailin fresh)

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Non Formulary 0.5% unit dose eye drops preservative free
Please prescribe generic carmellose as per formulary
 
Hydroxyethylcellulose  (Minims Artificial Tears)

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Non Formulary
 
Hydroxypropyl Guar  (Systane®)

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Non Formulary
 
Hypromellose  (Artelac)

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Non Formulary Artelac 0.32% eye drops
Artelac SDU 0.32% preservative free
 
Hypromellose  (Lumecare)

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Non Formulary Lumecare 0.3% eye drops
Lumecare tear drops 0.3% eye drops
 
Hypromellose  (Mandanal )

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Non Formulary 3% eye drops
 
Hypromellose  (Ocu-Lube)

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Non Formulary 0.3% eye drops preservative free
 
Hypromellose  (Softdrops)

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Non Formulary 0.3% eye drops
 
Hypromellose  (Tear-Lac)

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Non Formulary 0.3% eye drops preservative free
 
Hypromellose  (Vizulize)

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Non Formulary 0.3% eye drops
 
Hypromellose  (Xailin Hydrate)

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Non Formulary 0.3% eye drops preservative free
 
Hypromellose 0.3% eye drops

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Non Formulary Cheaper to prescribe 0.5%
 
Hypromellose 0.3% Preservative Free

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Non Formulary eye drops
 
Hypromellose 0.3% with Dextran 70 0.1%  (Tears naturale)

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Non Formulary Eye drops
Eye drops 0.4ml unit dose
 
Liquid Paraffin  (Lacri-Lube)

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Non Formulary

Lacri-Lube Eye Ointment 3.5g and 5g

Non formulary as Xalin Night is the preferred brand of liquid paraffin eye preparations

 
Optive Fusion

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Non Formulary The nearest equivalent formulary choice is Oxyal eye drops
 
Paraffin Yellow Soft

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Non Formulary Simple eye ointment
 
Pegaptanib Sodium  (Macugen)

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Non Formulary
Link  NICE TA155: guidance on pegaptanib in AMD (August 2008)
 
Polyvinyl Alcohol  (Liquifilm Tears or Sno Tears)

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Non Formulary

   Self Care Self Care Medicine-Available OTC for self care.

 
Polyvinyl Alcohol single dose units  (Liquifilm tears 1.4%)

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Non Formulary
 
Sodium Chloride

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Non Formulary
 
Sodium Chloride  (Minims Saline)

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Non Formulary
 
Sodium Chloride 0.9% Solutions

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Non Formulary
 
Sodium hyaluronate  (Artelac Splash)

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Non Formulary

0.2% eye drops 0.5ml unit dose

Formulary equivalent is Evolve HA eye drops which are preservative free

 
Sodium hyaluronate  (Blink intensive tears)

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Non Formulary

0.2% eye drops
0.2% preservative free single dose

Formulary equivalent are Evolve HA eye drops which are preservative free

 
Sodium hyaluronate  (Clinitas)

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Non Formulary Clinitas 0.4% eye drops 0.5ml unit dose
Clinitas multi 0.4% eye drops preservative free
 
Sodium Hyaluronate  (Hylo-Forte)

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Non Formulary

Formulary equivalent is Evolve HA preservative free eye drops.


May be used for some patients at Burton intolerant to certain ingredients in other preparations.

 
Sodium Hyaluronate  (Hylo-Tear)

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Non Formulary

Formulary equivalent are Evolve HA preservative free eye drops

 
Sodium hyaluronate  (Hy-Opti)

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Non Formulary

0.1% eye drops preservative free
0.2% eye drops preservative free

Formulary equivalent is Evolve HA preservative free eye drops

 
Sodium Hyaluronate  (Lubristil)

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Non Formulary

Sod Hyaluronate_Eye Dps 0.15%
Oxyal Sod Hyaluronate Eye Dps

Preservative Free

Preferred to prescribe Evolve HA preservative free eye drops

 
Sodium Hyaluronate  (Oxyal)

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Non Formulary

Oxyal eye drops 0.15%
 
 
 
 
 

 
Sodium Hyaluronate  (Vismed® Gel)

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Non Formulary
 
Sodium Hyaluronate  (Vismed multi)

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Non Formulary
 
Sodium hyaluronate (Hycosan Extra) 0.2% eye drops

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Non Formulary

Formulary equivalent is Evolve HA preservative free eye drops.

 
Sodium Hyaluronate (Hycosan) 0.1% eye drops

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Non Formulary

Formulary equivalent is Artelac rebalance preservative free eye drops 

 
Sodium hyaluronate (Hylo-Care)

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Non Formulary

Formulary equivalent is Artelac rebalance preservative free eye drops

 
Sodium hyaluronate (Hylo-Dual)

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Non Formulary Formulary equivalent is Oxyal eye drops or Xailin HA. Both are preservative free in the eye.
 
Sodium hyaluronate (Hylo-Fresh)

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Non Formulary Formulary equivalent is Oxyal eye drops or Xailin HA. Both are preservative free in the eye.
 
Sodium hyaluronate 0.15%, trehalose 3% eye drops  (Thealoz Duo®)

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Non Formulary
 
Sodium hyaluronate 0.15%, trehalose 3%, carbomer 0.25%  (Thealoz Duo gel )

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Non Formulary
 
Soybean oil unit dose eye drops  (Emustil®)

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Non Formulary
 
Verteporfin  (Visudyne)

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Non Formulary
 
Zinc Sulphate

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Non Formulary
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Red

Drugs which require special consideration. These are drugs for Consultant Prescribing ONLY. They should not be prescribed in Primary Care.  

Amber

Drugs that should be initiated by a Specialist but are suitable for continuation in Primary Care. For some drugs there may be a Ricad in place to aid the transition to primary care.  

Amber E

Drugs that should be initiated by a Specialist but are suitable for continuation in Primary Care but also require and ESCA (Shared Care Agreement)   

Green

Suitable first-line drugs for implementation in Primary Care  

On Formulary

South Staffs Formulary Choice  

netFormulary