South Staffordshire Joint Formulary Formulary


	South Staffordshire Joint Formulary Cannock Chase Clinical Commissioning Group East Staffordshire Clinical Commissioning Group South East Staffordshire and Seisdon Peninsula Clinical Commissioning Group Stafford and Surrounds Clinical Commissioning Group

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Formulary Chapter 2: Cardiovascular system - Full Chapter

02.02.03

Potassium-sparing diuretics and aldosterone antagonists

Amiloride Hydrochloride

Formulary

Amiloride 5mg Tablet

This item is expensive. If combining this drug with a loop diuretic consider combination preparation co-amilofruse.

02.02.03

Aldosterone antagonists

Spironolactone

First Choice

Spironolactone 25mg Tablet
Spironolactone 50mg Tablet
Spironolactone 100mg Tablet

Spironolactone has been shown to reduce symptoms and mortality in patients with Grade III or Grade IV heart failure. Careful monitoring of U&E's is required.

Eplerenone

Formulary

Eplerenone 25mg Tablet
Eplerenone 50mg Tablet

For patients with left ventricular dysfunction following myocardial infarction (start therapy within 3-14 days of the event, as per BNF).
Careful monitoring of U&E's is required
Consider changing to spironolactione once stable.

Once patient in stabilised prescribing can continue in primary care. A RICad or prescribing supporting information will be provided

NICE NG106: Chronic heart failure in adults: diagnosis and management

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Non Formulary Items

Spironolactone (Aldactone^®)

Non Formulary

Brand is non formulary as less cost effective. Please prescribe generically

Triamterene (Dytac^®)

Non Formulary

Key

	Notes
	Section Title (top level)
	Section Title (sub level)
	First Choice item
	Non Formulary section
	Restricted Drug
	Unlicensed
	Display tracking information
	Link to adult BNF
	Link to children's BNF
	Link to SPCs
	Scottish Medicines Consortium

	Cytotoxic Drug
	Controlled Drug
	High Cost Medicine
	Cancer Drugs Fund
	NHS England
	Homecare
	CCG

Traffic Light Status Information

Status	Description
	Drugs which require special consideration. These are drugs for Consultant Prescribing ONLY. They should not be prescribed in Primary Care.
	Drugs that should be initiated by a Specialist but are suitable for continuation in Primary Care. For some drugs there may be a Ricad in place to aid the transition to primary care.
	Drugs that should be initiated by a Specialist but are suitable for continuation in Primary Care but also require and ESCA (Shared Care Agreement)
	Suitable first-line drugs for implementation in Primary Care
	South Staffs Formulary Choice