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South Staffordshire Joint Formulary
Cannock Chase Clinical Commissioning Group
East Staffordshire Clinical Commissioning Group
South East Staffordshire and Seisdon Peninsula Clinical Commissioning Group
Stafford and Surrounds Clinical Commissioning Group
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 Formulary Chapter 4: Central nervous system - Full Chapter
04.03.03  Expand sub section  Selective serotonin re-uptake inhibitors
Sertraline
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First Choice
Green
Sertraline HCl Tablet 50mg
Sertraline HCl Tablet 100mg
 
Citalopram
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First Choice
Green
Citalopram Hydrobromide Tablet 10mg
Citalopram Hydrobromide Tablet 20mg
Citalopram Hydrobromide Tablet 40mg
Citalopram HCl Oral Drops 40mg/ml S/F

Cost effective choice in patients where QT interval prolongation is not an issue (see MHRA advice below for detail) Maximum daily dose 40 mg for adults; 20 mg for patients older than 65 years; and 20 mg for those with hepatic impairment. 
Escitalopram (Cipralex)
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Formulary
Green

Escitalopram Tablet 5mg
Escitalopram Tablet 10mg
Escitalopram Tablet 20mg
Escitalopram Oral Drops 10mg/ml S/F


See MHRA advice on QT prolongation. Maximum daily dose 20 mg for adults; 10 mg for patients older than 65 years; and 10 mg for those with hepatic impairment.

 
Link  Citalopram and escitalopram: QT interval prolongation
   
Fluoxetine
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Formulary
Green
Treatment in Adults

Fluoxetine HCl Capsule 20mg
Fluoxetine 20mg orodispersible tablets

Use the orodispersible tablets where there are swallowing difficulties or patient is on a 10mg dose as the tablet can be divided into equal halves to get the correct dose. This is much more cost effective then the oral solution 
   
Fluoxetine
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Formulary
Amber E

Treatment in Adolescents

Fluoxetine HCl Capsule 20mg
Fluoxetine Liquid 20mg/5ml (Prescribe Liquid for doses less than 20mg)

See link below for ESCA's. 

Please use the ESCA's under the title Agreements - South Staffordshire CCG Locality

 
Link  Essential Shared Care Aggreements - SSSFT
   
Paroxetine
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Formulary
Amber
Paroxetine HCl Tablet 20mg
Paroxetine HCl Tablet 30mg
Paroxetine Oral Suspension 10mg/5ml SF

Withdrawal syndrome is more common with paroxetine - Royal College of Psychiatrists 
Link  Coming off antidepressants
   
Vortioxetine (Brintellix)
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Formulary
Amber

5mg Tablets
10mg Tablets
20mg Tablets

 

Vortioxetine is recommended as an option for treating major depressive

episodes in adults whose condition has responded inadequately to

2 antidepressants within the current episode.

 

 
Link  TA367 - Vortioxetine for treating major depressive episodes
   
 ....
 Non Formulary Items
Fluoxetine  (Prozac®)

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Non Formulary
 
Fluvoxamine Maleate  (Faverin®)

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Non Formulary
 
Fluvoxamine Maleate  (Fluvoxamine®)

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Non Formulary
 
Paroxetine  (Seroxat®)

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Non Formulary
 
Sertraline  (Lustral®)

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Non Formulary
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Red

Drugs which require special consideration. These are drugs for Consultant Prescribing ONLY. They should not be prescribed in Primary Care.  

Amber

Drugs that should be initiated by a Specialist but are suitable for continuation in Primary Care. For some drugs there may be a Ricad in place to aid the transition to primary care.  

Amber E

Drugs that should be initiated by a Specialist but are suitable for continuation in Primary Care but also require and ESCA (Shared Care Agreement)   

Green

Suitable first-line drugs for implementation in Primary Care  

On Formulary

South Staffs Formulary Choice  

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