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South Staffordshire Joint Formulary
Cannock Chase Clinical Commissioning Group
East Staffordshire Clinical Commissioning Group
South East Staffordshire and Seisdon Peninsula Clinical Commissioning Group
Stafford and Surrounds Clinical Commissioning Group
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 Formulary Chapter 6: Endocrine system - Full Chapter
06.06.02  Expand sub section  Bisphosphonates and other drugs affecting bone metabolism
 link Link    NICE CG146: Osteoporosis: assessing the risk of fragility fracture
 link Link    NICE TA160 Osteoporosis - primary prevention
 link Link    NICE TA161: Osteoporosis - secondary prevention (including strontium ranelate)
06.06.02  Expand sub section  Bisphosphonates
Alendronic Acid
View adult BNF View SPC online View childrens BNF  Track Changes 		First Choice
Green 		First Line Choice - Prescribe generically as 70mg once weekly. Combination products with Vitamin D are not on the formulary. People at risk of osteoporosis need to maintain an adequate intake of Calcium and Vitamin D; Vitamin D dosage should be 800iu per day. 
Link  NICE TA464: Bisphosphonates for treating osteoporosis
   
Ibandronic Acid  (Injection)
View adult BNF View SPC online View childrens BNF  Track Changes 		Formulary
Amber

Ibandronic acid 3mg/3ml solution for injection pre-filled syringes

Licensed for osteoporosis for Specialist Initiation

 
Link  NICE TA464 - Bisphosphonates for treating osteoporosis
   
Risedronate
View adult BNF View SPC online View childrens BNF  Track Changes 		Formulary
Green 		People at risk of osteoporosis need to maintain an adequate intake of Calcium and Vitamin D; Vitamin D dosage should be 800iu per day. 
Link  NICE TA464: Bisphosphonates for treating osteoporosis
   
Alendronic Acid Effervescent tablets (Binosto)
View adult BNF View SPC online View childrens BNF  Track Changes 		Formulary
Green 		70mg effervescent Tablets

Please note these are for patients with swallowing difficulties only.

People at risk of osteoporosis need to maintain an adequate intake of Calcium and Vitamin D; Vitamin D dosage should be 800iu per day. 
Link  NICE TA464 - Bisphosphonates for treating osteoporosis
   
Ibandronic Acid (Oral)
View adult BNF View SPC online View childrens BNF  Track Changes 		Formulary
Amber

Ibandronic acid 50mg tablets

Ibandronic acid 150mg tablets
 
Therapeutic indications Ibandronic acid is indicated in adults for prevention of skeletal events (pathological fractures, bone complications requiring radiotherapy or surgery) in patients with breast cancer and bone metastases.

People at risk of osteoporosis need to maintain an adequate intake of Calcium and Vitamin D; Vitamin D dosage should be 800iu per day .

 
Link  NICE TA464: Bisphosphonates for treating osteoporosis
   
Ibandronic acid IV infusion (Bondronat®)
View adult BNF View SPC online View childrens BNF  Track Changes 		Formulary
Red 		 
   
Sodium Clodronate
View adult BNF View SPC online View childrens BNF  Track Changes 		Formulary
Amber 		 
   
Zoledronic Acid
View adult BNF View SPC online View childrens BNF  Track Changes 		Formulary
Red 		 
   
Disodium Pamidronate
View adult BNF View SPC online View childrens BNF  Track Changes 		Restricted Drug Restricted
Red 		 
   
 link Link    UKMI Q&A: Gastric adverse events influencing the choice of bisphosphonate?
 link Link    UKMI Q&A: Proton pump inhibitor interaction with bisphosphonates?
 link Link    UKMI Q&A: Renal impairment and use of oral bisphosphonates
06.06.02  Expand sub section  Denosumab
 ....
 Non Formulary Items
Alendronic Acid  (Fosamax®)

View adult BNF View SPC online View childrens BNF 		Non Formulary
 
Alendronic Acid  (Fosamax® Once Weekly)

View adult BNF View SPC online View childrens BNF 		Non Formulary
 
Alendronic Acid with colecalciferol  (Fosavance®)

View adult BNF View SPC online View childrens BNF 		Non Formulary
 
Disodium Etidronate  (Didronel PMO®)

View adult BNF View SPC online View childrens BNF 		Non Formulary
 
Disodium Etidronate  (Didronel®)

View adult BNF View SPC online View childrens BNF 		Non Formulary
 
Disodium Pamidronate  (Aredia® Dry Powder)

View adult BNF View SPC online View childrens BNF 		Non Formulary
 
Risedronate

View adult BNF View SPC online View childrens BNF 		Non Formulary
 
Sodium Clodronate  (Clasteon®)

View adult BNF View SPC online View childrens BNF 		Non Formulary
 
Tiludronic Acid  (Skelid®)

View adult BNF View SPC online View childrens BNF 		Non Formulary
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
 Display tracking information
click to search medicines.org.uk
 Link to adult BNF
click to search medicines.org.uk
 Link to children's BNF
click to search medicines.org.uk
 Link to SPCs
SMC
 Scottish Medicines Consortium
Cytotoxic Drug
 Cytotoxic Drug
CD
 Controlled Drug
High Cost Medicine
 High Cost Medicine
Cancer Drugs Fund
 Cancer Drugs Fund
NHSE
 NHS England
Homecare
 Homecare
CCG
 CCG

Traffic Light Status Information

Status Description

Red

 Drugs which require special consideration. These are drugs for Consultant Prescribing ONLY. They should not be prescribed in Primary Care.  

Amber

 Drugs that should be initiated by a Specialist but are suitable for continuation in Primary Care. For some drugs there may be a Ricad in place to aid the transition to primary care.  

Amber E

 Drugs that should be initiated by a Specialist but are suitable for continuation in Primary Care but also require and ESCA (Shared Care Agreement)   

Green

 Suitable first-line drugs for implementation in Primary Care  

On Formulary

 South Staffs Formulary Choice  

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