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South Staffordshire Joint Formulary
Cannock Chase Clinical Commissioning Group
East Staffordshire Clinical Commissioning Group
South East Staffordshire and Seisdon Peninsula Clinical Commissioning Group
Stafford and Surrounds Clinical Commissioning Group
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 Formulary Chapter 8: Malignant disease and immunosuppression - Full Chapter
08.03.04.02  Expand sub section  Prostate cancer and gonadorelin analogues
08.03.04.02  Expand sub section  Gonadorelin analogues
08.03.04.02  Expand sub section  Anti-androgens
Leuprorelin Acetate (Prostap SR)
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First Choice
Amber

This is the preferred Injectable LHRH Agonist (or GnRH Analogue)

Prostap SR 3.75mg - monthly

Indications:

  • Prostate cancer
  • Endometriosis
  • Endometrial preparation prior to intrauterine surgery
  • Preoperative management of Uterine fibroids
 
Leuprorelin Acetate (Prostap 3)
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First Choice
Amber

This is the preferred Injectable LHRH Agonist (or GnRH Analogue)

Prostap 3 (11.25mg) - 3 monthly

Indications:

  • Prostate cancer
  • Endometriosis
  •   Central Precocious Puberty (CPP) in girls under 9 years of age, boys under 10 years of age

 

 
Triptorelin- Decapeptyl SR
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First Choice
Amber

Decapeptyl SR 3mg - monthly

Indications:

  • Prostate cancer
  • Endometriosis & uterine fibroids
  • Breast cancer

Decapeptyl SR 11.25mg - 3 monthly

Indications:

  • Prostate cancer
  • Central Precocious puberty (CPP) onset before 8 years in girls and 10 years in boys.

Decapeptyl SR 22.5mg - 6 monthly

Indications:

  • Prostate cancer
  • Endometriosis
  • Central Precocious puberty (CPP) in children 2 years and older with an onset of CPP before 8 years in girls and 10 years in boys).
 
Goserelin (Zoladex)
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Second Choice
Amber

Zoladex 3.6 mg Implant - monthly

Indications:

  • Prostate cancer
  • Breast cancer
  • Endometriosis
  • Endometrial thinning
  • Uterine fibroids
  • Assisted reproduction

 

 
Link  MTRAC - Goserelin for the treatment of prostate cancer
   
Goserelin (Zoladex LA)
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Second Choice
Amber

Zoladex LA 10.8mg implant - 3 monthly

Indications:

  • Prostate cancer
 
   
Bicalutamide
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Formulary
Amber
 
Link  MTRAC - Bicalutamide (Casodex) for the treatment of Prostate Cancer
   
Abiraterone Acetate
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Formulary
Red

This is an NHS England Specialised Commissioning Drug for Hormone Antagonists

 

 
Link  NICE TA259 - Abiraterone for castration-resistant metastatic prostate cancer previously treated with a docetaxel-containing regimen
Link  NICE TA387 Abiraterone for treating metastatic hormone-relapsed prostate cancer before chemotherapy is indicated
   
Cyproterone Acetate
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Formulary
Amber
 
   
Enzalutamide
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Formulary
Red

This is an NHS England Specialised Commissioning Drug for Cancer

 
Link  NICE TA316: Enzalutamide for metastatic hormone‑relapsed prostate cancer previously treated with a docetaxel‑containing regimen
Link  NICE TA377: Enzalutamide for treating metastatic hormone-relapsed prostate cancer before chemotherapy is indicated
Link  Restrictions in use of cyproterone acetate due to risk of meningioma (April 2020)
   
 ....
 Non Formulary Items
Buserelin

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Non Formulary
 
Flutamide

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Non Formulary
 
Flutamide  (Drogenil®)

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Non Formulary
 
Triptorelin  (Gonapeptyl Depot)

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Non Formulary
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
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Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Red

Drugs which require special consideration. These are drugs for Consultant Prescribing ONLY. They should not be prescribed in Primary Care.  

Amber

Drugs that should be initiated by a Specialist but are suitable for continuation in Primary Care. For some drugs there may be a Ricad in place to aid the transition to primary care.  

Amber E

Drugs that should be initiated by a Specialist but are suitable for continuation in Primary Care but also require and ESCA (Shared Care Agreement)   

Green

Suitable first-line drugs for implementation in Primary Care  

On Formulary

South Staffs Formulary Choice  

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